Staff Profile

Biography

Teaching Areas & Research Interests

• Personalized medicine and targeted therapy
• Functional study of oncogene and tumor suppressor genes
• Drug development

Selected Publications

Book Chapters

• Lui K and Wong MCS. (2021) Genetic Testing for Personalized medicine and Limitations of the Current Medical Practice in Public Health. Routledge Handbook of Public Health and the Community. Routledge, p104-115.

Journal Articles

• Chen L, Niu D, Lee CH, Yao Y, Lui K, Ho KM, Li P. (2016) Amphiphilic Core-Shell Nanocomposite Particles for Enhanced Magnetic Resonance Imaging. Particles & Particle Systems Characterization. 33:756-763.
• Lui K, Huang Y, Sheikh SM, Cheung KK, Tam WY, Sun KT, Cheng KM, Ng WWM, Loh AWK. (2023) The oncogenic potential of Rab-like protein 1A (RBEL1A) GTPase: The first review of RBEL1A research with future research directions and challenges. 14:3214-3226.
• Lui K, Sheikh MS, Huang Y. (2015) Negative regulation of p53 oligomerization by Ras superfamily protein RBEL1A. Genes Cancer. 6:307-316.
• Zhang M, Qiu Q, Li Z, Sachdeva M, Min H, Cardona DM, DeLaney TF, Han T, Ma Y, Luo L, Ilkayeva O, Lui K, Nichols AG, Newgard CB, Kastan MB, Rathmell JC, Dewhirst MW, Kirsch DG. (2015) HIF-1a regulates the response of primary sarcomas to radiation therapy through a cell autonomous mechanism. Radiation Research. Radiation Research. 183:594-609.
• Lui K, An J, Montalbano J, Shi J, Corcoran C, He Q, Sheikh MS, Huang Y. (2013) Negative regulator of p53 by Ras superfamily protein RBEL1A. Journal of Cell Science. 126:2436-45.
• Sun H, Jiang LY, Luo X, Jin W, He Q, An J, Lui K, Shi J, Rong R, Sun W, Lucchesi C, Liu Y, Sheikh MS, Huang Y. (2013) Potential tumor-suppressive role of monoglyceride lipase in human colorectal cancer. Oncogene. 32:234-41.
• An J, Shi J, He Q, Lui K, Liu Y, Huang Y, Sheikh MS. (2012) CHCM1/CHCHD6, a Novel DNA-damage Regulated Protein Linked to Maintaining Mitochondrial Cristae Morphology. J Biol Chem, 287: 7411-26.
• Lui K, Huang Y. (2009) RanGTPase: A Key Regulator of Nucleocytoplasmic Trafficking. Journal of Molecular and Cellular Pharmacology. 3:148-156.
• Montalbano J, Lui K, Sheikh MS, Huang Y. (2009) Identification of characterization of RBEL1 subfamily of GTPases in the Ras superfamily involved in cell growth regulation. J Biol Chem, 284:18129-42.
• Masri S, Lui K, Phung S, Ye J, Zhou D, Wang X, Chen S. (2009) Characterization of the weak estrogen receptor alpha agonistic activity of exemestane. Breast Cancer Res Treat. 116:461-70.
• Adams LS, Phung S, Wu X, Lui K, Chen S. (2008) White button mushroom (Agaricus bisporus) exhibits antiproliferative and proapoptotic properties and inhibits prostate tumor growth in athymic mice. Nutr Cancer. 60:744-56.
• Lui K, Tamura T, Mori T, Zhou D, Chen S. (2008) MCF-7aro/ERE, a novel cell line for rapid screening of aromatase inhibitors, ERalpha ligands and ERRalpha ligands. Biochem Pharmacol. 76:208-15.
• Zhou D, Ye JJ, Li YP, Lui K, and Chen S. (2006) The molecular basis of the interaction between the proline-rich SH3-binding motif of PNRC and estrogen receptor alpha. Nucleic Acids Res. 20: 5974-86.
• Lui K, Huang Y, Choi HL, Yu S, Wong KB, Chen S and Chan FL. (2006) Molecular Cloning and Functional Study of Rat Estrogen Receptor-Related in rat Prostatic cells. Prostate. 15:1600-19.
• Chen S, Phung S, Kwok S, Ye J, Hur G, Oh S, Smith D, Yuan Y-C, Karlsberg K, Lui K. (2005) Chemopreventive properties of mushrooms against breast cancer and prostate cancer. International Journal of Medicinal Mushrooms. 7: 342-343.
• Expression Study of Estrogen Receptor-related Receptors and Steroid Hormone Receptors in Human Prostatic Cells. Hormonal Carcinogensis IV, Springer, p501-507.
• Kwong J, Lui K, Chan PS, Ho SM, Wong YC, Xuan JW and Chan FL. (2003) An Expression Study of Three Secretory Proteins (Prostatic Secretory Protein of 94 Amino Acids, Probasin, and Seminal Vesicle Secretion II) in Dysplastic and Neoplastic Rat Prostates. Prostate. 56:81-97.

Further Information

Link to Google Scholar page

Modified Date: 07 May, 2024
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